The interconnected network of oral and gastrointestinal tract microbiomes present unique opportunities for advancing human health therapy.
The oral and gastrointestinal tract microorganisms constitute the bulk of the overall human microbial load.
It is becoming clear that many and perhaps most chronic conditions have a microbial involvement.
We are dependent on our microbiomes to perform many functions that are essential to our health.
The repercussions of impaired oral health on overall health are established
Periodontal disease is accepted by the medical community for its role in cardiovascular problems and diabetes,
The periodontal disease is a risk factor for diabetes, heart disease, respiratory disease, stroke, premature births, and low birth weights.
Oral health problems in children can lead to attention deficits, difficulty in school, and dietary and sleep issues. Also, oral health problems in older adults can lead to disability and reduction in mobility.
Since the mouth is the gateway to the digestive tract, it should not be surprising that what happens in the oral cavity impacts the rest of the body (and vice versa, as in the case of diabetes).